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‘A mouse can’t tell us what works’: UK scientists to grow miniature human organs for drug testing

Organoids and tissues grown from human cells promise more accurate results, with £20m Cambridge project to create standardised models

Miniature human organs and other tissues are to be grown from NHS patients’ cells in a drive to improve medicine testing and reduce the number of animals used in drug development.

Scientists will use the clumps of tissue to learn how diseases vary between patients, helping them identify which treatments are best for different people based on the particular pathology underlying their condition.

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British man with dementia told to leave Sweden after losing migration case

Exclusive: Horace Mason, 74, who has lived in Sweden for 25 years, faces being deported after court ruling

A 74-year-old British man who has been living in Sweden for 25 years who needs round-the-clock care for dementia has been given 10 days to leave the country after he lost a post-Brexit migration court case.

The deportation order comes after a Swedish court ruling in July that the government’s drive to reduce immigration trumped the needs of a man in full-time care.

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Ceuta showed just how easily Europe can be divided

The migrant influx prompted recriminations and a tit-for-tat dispute between Italy and Spain. Putin, Erdoğan and others will have taken note

Within hours of the first pictures of tens of thousands of migrants swimming the short distance from Morocco to the Spanish north African enclave of Ceuta hitting social media on 30 July, 22 European Union leaders, the Trump administration and Israel had piled on to criticise Madrid.

The outbreak of hysteria and recrimination was a case study in 21st-century politics, driven by real-time images in a media echo chamber where populists set the agenda on migration, propagating fear, prejudice and demagogic proposals. Above all, the kneejerk reactions undermined trust between European allies and dealt a setback to EU efforts to jointly manage migration, counter people-smuggling and resist the weaponisation of migrants by non-EU countries.

Paul Taylor is a senior visiting fellow at the European Policy Centre

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‘I turned down Gandhi because I’m terrified of snakes’: the amazing movie memories of Bruce Dern

Famed for playing loners, cranks and wayward angels, the Hollywood star is now a wolfish 90 – but he still jogs daily. As he takes his latest film to Edinburgh, we meet the man Hitchcock called ‘the golden calf’

‘Can you take another story?” asks the veteran actor Bruce Dern towards the end of our talk, as though every tale is a drink and the landlord has called last orders. He doesn’t want to keep me and knows we’re running out of time. It’s just that one memory sparks another and these tales won’t tell themselves. He says that the next one is a doozy. “It’s about Marilyn Monroe.”

Throw out all the questions and turn the clocks to the wall. One does not interview Dern so much as say hello, hit record and sit back. The man began his career acting alongside Montgomery Clift and Mary Astor and has collaborated with everyone from John Wayne to Tom Hanks, Hitchcock to Tarantino. He’s the lawless survivor of American movies, blown in from the past, and talking 19 to the dozen. “I’m 90 fucking years old,” he tells me. “So I’m not going to be around to see all this AI shit or whatever. But I don’t consider myself old. I still walk and jog every day.”

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‘It’s going to be spectacular’: Millions flock to Spain seeking best view of total solar eclipse

Eclipse chasers, tourists and astronomers searching for the clearest skies to watch the two minutes of totality

The online forums are abuzz as people debate potential cloud cover and trade tips on the best viewing points. Hours before wide swathes of Spain were set to experience the country’s first total solar eclipse in more than a century, the excitement was palpable.

“It’s going to be spectacular,” said César González, an astronomer and science communicator at the Madrid Planetarium. “A total solar eclipse is one of the best spectacles in nature.”

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Mayflies review – Manchester’s Haçienda roars back to life in an Edinburgh warehouse

Rear Warehouse, Brown’s of Leith, Edinburgh
Two men look back on their hedonistic past from a sobering present in Grid Iron’s adaptation of Andrew O’Hagan’s novel

The site-specific specialists at Edinburgh’s Grid Iron company could have gone for a number of locations to suit an adaptation of Andrew O’Hagan’s semi-autobiographical novel. Perhaps a squalid mid-80s flat to match the formative years of Jimmy Collins, the book’s narrator, and Tully Dawson, his lifelong best friend. Or a caravan park to reflect their Ayrshire holiday escape. More poignantly, they could have found a clinic to echo the novel’s slow journey to Dignitas, where the grownup Tully chooses to end his life after a terminal cancer diagnosis.

Instead, adapter and director Ben Harrison has homed in on the book’s central motif: the teenage trip in 1986 to Manchester’s G-Mex for the Festival of the Tenth Summer followed by a night in the Haçienda. That brings us to a warehouse in Leith, to evoke the flavour of that Thatcher-era moment when heavy industry transitioned to the leisure economy.

At Rear Warehouse, Brown’s of Leith, Edinburgh, until 30 August

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岩崎・笹内川

TRUE 2 DEATH has added a photo to the pool:

岩崎・笹内川

There’s something comforting about evenings like this in Iwasaki. The last light lingering over the hills, a car making its way across the bridge over the Sasanai River. Quietly passing through the village.
Iwasaki is more than just a place I visit. I have family here, and over the past 25+ years I’ve been fortunate enough to spend weeks at a time in this small village along the Aomori coast. It’shome away from home. Nothing extraordinary needs to happen here. Sometimes just standing by the river and watching an ordinary evening unfold is enough.

Iwasaki Village, Aomori Prefecture, Japan
June 2026

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RIP John Crowley

John Crowley author of many MeFi favourite books such as Little, Big and The Aegypt cycle has passed away.