The Guardian

Latest news, sport, business, comment, analysis and reviews from the Guardian, the world's leading liberal voice

Can antihistamines really help with PMDD and menopausal symptoms?

Debilitating symptoms lead some to try over-the-counter medications Allegra and Pepcid due to a social media trend

Premenstrual dysphoric disorder (PMDD) and menopause can come with debilitating symptoms, like intense emotional changes and exhaustion.

All over social media, women are claiming that a simple hack has helped enormously: a combination of two over-the-counter medications, both antihistamines – typically, the name brands Pepcid AC and Allegra.

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Alien: Isolation 2 – another strong female protagonist stalked in a terrifying new world

Creative Assembly could strike gold again with this follow-up to their fan-favourite, film-inspired game … if you’re brave enough to venture outdoors

Alien: Isolation redefined Alien games on its release in 2014, bringing the original taut, haunted house theme of the first movie to fans who had mostly been fed action-packed shooters. Cowering under desks and inside lockers wasn’t a new thing; being hunted by an intelligent and lethal xenomorph that could spring down from a duct at any moment was.

“I was thinking about what we could do for a sequel while we were still finishing the first game,” reveals Creative Assembly’s Alistair Hope, creative lead on Alien: Isolation and its sequel. “But we didn’t actually start the project until around the time of the 10th anniversary. We’ve seen the response grow over time, watching [Alien: Isolation] continue to find new players, even though it’s a relatively old game. And they’re surprised there isn’t a sequel.”

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‘Murakami saw his book come alive!’: the Japanese company bringing the author’s science fiction masterpiece to the stage

A play based on the writer’s dreamlike novel Hard-Boiled Wonderland and the End of the World is touring the world, riding a wave of interest in Japanese culture. Its creators talk about how they adapted the famously cryptic tale

Tatsuya Fujiwara is no stranger to London’s Barbican theatre. It was here nearly 30 years ago that one of Japan’s biggest film stars, now 44, made his stage debut. He was just 15, plucked out of an audition of more than 5,000 hopeful youngsters by the revered theatre director Yukio Ninagawa for his play Shintoku-Maru. It kickstarted Fujiwara’s career, and three years later he landed a role in the cult dystopian film Battle Royale, going on to star in hit TV dramas and blockbuster films, all the while continuing to perform in Ninagawa’s acclaimed productions.

Now, Fujiwara returns to where it all began, to perform in a stage adaptation of Haruki Murakami’s science fiction novel Hard-Boiled Wonderland and the End of the World. The story alternates between two seemingly unrelated narratives: a cyberpunk thriller set in Tokyo, and a surreal fantasy that unfolds within a mysterious walled town. Directed by the French choreographer Philippe Decouflé, the play premiered in Tokyo in January, toured Japan until March, then Singapore in April. After the Barbican run this autumn, the tour will wrap up in Paris.

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I’m a neuroscientist. Here’s why our brains need pop concerts | Bala Subramaniam

Attending a Nick Jonas show with my kids was an invitation to ‘collective effervescence’. We need these shared experiences now more than ever

Three years ago, I agreed to accompany my children to a Nick Jonas concert. The appeal of the Jonas Brothers, and in this case only one of them, was unfamiliar territory.

The concert happened to land on a particularly inconvenient day. As I sprinted out of the hospital, my mind was filled with the “what if’s” and “should haves” about our work that day.

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‘We get 200 tourists a day’: when your house becomes a TV star

What’s it like to live on the set of a soap opera? Or above Ted Lasso’s favourite pub? The residents of the homes made famous by hit TV shows tell all

Half the world recognises the apartment that Carrie Bradshaw lives in. Or the New Jersey mansion where Tony Soprano ate, slept and obsessed over the ducks in his swimming pool. In the 1990s, if you asked a good chunk of the global population where Will Smith lived, they would instantly picture a huge, white abode in Bel Air.

For the real people who call those places home, this can be an issue.

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Volkskrant.nl biedt het laatste nieuws, opinie en achtergronden

De inzet voor kansengelijkheid mag niet stoppen na het verlaten van het onderwijs

Polen verijdelt Russische poging om Amerikaanse Oekraïner te vermoorden

Opnieuw een weerrecord: voor de negende dag dit jaar is het boven de 35 graden

Toyokawa, Osaka, Japan 豊川、大阪

Mr Mikage (ミスター御影) posted a photo:

Toyokawa, Osaka, Japan 豊川、大阪

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Peter Kernwein posted a photo:

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Peter Kernwein posted a photo:

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Peter Kernwein posted a photo:

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Peter Kernwein posted a photo:

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Peter Kernwein posted a photo:

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Wel.nl

Minder lezen, Meer weten.

Hitteplan vanaf zaterdag niet meer actief in acht provincies

BILTHOVEN (ANP) - Het Nationaal Hitteplan is vanaf zaterdag om 08.00 uur niet langer van kracht in acht provincies, meldt het RIVM. Het plan geldt dan nog wel in Limburg, Noord-Brabant, Gelderland en Overijssel, waar een hittekracht van 7 tot 8 wordt verwacht. In die vier provincies eindigt het hitteplan zondag om 08.00 uur.

Het Nationaal Hitteplan werd woensdag geactiveerd, voor de vierde keer dit jaar. Met het hitteplan krijgen allerlei organisaties, professionals en mantelzorgers informatie over de verwachte hitte. Die kunnen dan maatregelen nemen voor kwetsbare mensen.


Spanje verlengt levensduur van grootste kerncentrale

MADRID (ANP/AFP/RTR) - De Spaanse regering heeft de levensduur van de grootste kerncentrale van het land verlengd om zo minder blootgesteld te zijn aan onrust op de energiemarkt, mede door de oorlog in het Midden-Oosten. De Almaraz-kerncentrale in de zuidwestelijke regio Extremadura blijft nu tot medio 2030 operationeel.

Het was eigenlijk de bedoeling dat volgend jaar zou worden begonnen met het stilleggen van de centrale als onderdeel van de Spaanse plannen om in 2035 helemaal af te stappen van kernenergie. Maar de energiebedrijven en eigenaren van de centrale, Iberdrola, Endesa en Naturgy, hadden vorig jaar om verlenging van de operationele levensduur gevraagd. Daar is nu mee ingestemd.

De Almaraz-centrale heeft twee reactoren en is goed voor ongeveer 7 procent van de stroomvoorziening van Spanje. In totaal heeft het land vijf actieve centrales. De discussie rond kernenergie laaide ook op na de enorme stroomstoring in Spanje en buurland Portugal in april vorig jaar.


Kabinet tegen boeren na ongeval: demonstreer niet op snelwegen

DEN HAAG (ANP) - Het kabinet roept boeren op niet met tractoren op snelwegen te demonstreren. Minister Pieter Heerma (Binnenlandse Zaken, CDA), die gaat over het demonstratierecht, doet die oproep nadat er vrijdag twee doden waren gevallen op de A59. Zij kwamen om bij een botsing in de staart van een file, die het gevolg was van trekkers op de snelweg.

Boeren demonstreren in Den Bosch tegen de stikstofplannen van het kabinet, en het intrekken van vergunningen van kippenboeren. Het lokale gezag gedoogde de demonstratie op de snelweg. Donderdag verwees het ministerie van Justitie en Veiligheid ook naar het lokale gezag voor het handhaven van de regels.


The Register

Biting the hand that feeds IT — Enterprise Technology News and Analysis

TalkTalk Business and ARO to borg into UK tech services giant

TalkTalk Business and UK technology services biz ARO plan to merge, creating what they say will be one of the country's largest communications and managed services providers. The pair claim the combined organization will be "uniquely positioned" to serve as a single technology partner for British firms pursuing digital transformation. It will have annual revenue of about £200 million ($270 million) and a combined customer base of more than 70,000 companies. Analyst firm Megabuyte noted that ARO, formerly known as Arrow, is the larger of the two businesses by earnings. However, the vast majority of the combined customer base will comprise TalkTalk Business's small-business clients, with the remainder mainly ARO enterprise customers. Megabuyte expects fixed-line and mobile communications and connectivity to generate most of the combined revenue – about £130 million ($176 million) – with IT and cybersecurity services providing the remainder. Megabuyte said the immediate priority would be integrating the businesses and finding opportunities to sell their services across the combined customer base. "One can see why the deal is being sold in terms of cross-sell, with relatively little overlap in terms of customers and products. TalkTalk Business has a large base of small business customers who should be receptive to ARO's mobile and Microsoft offerings, as well as other IT and cyber services," says chief analyst Philip Carse. TalkTalk Business completed its separation from the wider TalkTalk Group earlier this year as it sought to expand as an independent managed network provider. It recently acquired Planet IT, a service desk biz selling IT support and professional services. ARO provides cloud, cybersecurity, and datacenter services and is a Microsoft Solutions Partner. The two firms describe their operations as highly complementary. The deal remains subject to approval under the UK's National Security and Investment Act (NSIA), apparently because ARO supplies some government customers, and is expected to close by the end of the summer. Initially, both businesses will retain their existing brands and offices while the companies develop their integration plans. The implication there is that there could be a shake-out of duplicate products and staff roles coming later, as often happens with corporate mergers. We asked what the combined business would be called and who would lead it, but the companies declined to answer. "This is a defining moment for both ARO and TalkTalk Business," claimed ARO chief Ciaran Rafferty. "By bringing together our complementary strengths, we are creating a stronger partner with broader capabilities, deeper expertise and greater capacity to invest in innovation, service delivery and long-term customer success." TalkTalk Business CEO Ruth Kennedy said it represents a key step in the firm's ambitions to become a leading managed services provider. "The market is evolving rapidly, with organizations increasingly seeking technology partners that can combine strategic expertise, operational excellence and broad service capabilities at scale," she commented. ®

The Moscow Times - Independent News From Russia

The Moscow Times offers everything you need to know about Russia: Breaking news, top stories, business, analysis, opinion, multimedia

Russia Dismisses Calls for Black Sea Ceasefire

The Foreign Ministry said it saw no grounds for "half-measures" that would offer a respite to Ukrainian forces.

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Getting more water is another thing entirely

Glen Canyon Dam and Lake Powell sit near the center of the Colorado River system, upstream from Hoover Dam and Lake Mead. Together those reservoirs store the water that cities, farms, and power plants across the Southwest depend on. Now the entire system is being pushed past its limits, and Lake Powell is where the cracks are really starting to show.